Kategori: Genome Analyzer
HIV Treatment
Although global commitment to control the HIV/AIDS pandemic has increased significantly in recent years, the virus continues to spread with alarming and increasing speed. By the end of 2005, an estimated 40 million people worldwide were living with HIV infection or disease, a notable rise from the 35 million infected with HIV in 2001 (UNAIDS…
HIV Genotype and Phenotype Testing
Development of drug resistance to antiretroviral therapy HIV Genotype and Phenotype Testing- Human immunodeficiency virus (HIV) replicates rapidly, particularly in response to antiretroviral (ARV) therapies. These replications are a result of substitutions in the viral protease, reverse transcriptase, or integrase enzymes which are targeted by various ARV drugs that can lead to drug-resistant mutations (quasi…
Illumina Sequencing
In the mid-1990s, scientists at Cambridge, Shankar Balasubramanian and David Klenerman, developed methods to produce high-quality reads of much greater data size at a reduced cost. In this method single DNA molecules are attached to a flat surface, amplified in situ, and sequenced using fluorescent reversible terminator deoxyribonucleotides. The florescent signals generated during the reaction…