Tag: ilumina

In the mid-1990s, scientists at Cambridge, Shankar Balasubramanian and David Klenerman, developed methods to produce high-quality reads of much greater data size at a reduced cost. In this method single DNA molecules are attached to a flat surface, amplified in situ, and sequenced using fluorescent reversible terminator deoxyribonucleotides. The florescent signals generated during the reaction…